Rising demand-1

In the previous experiment CA-2 was exposed to rising demand for its product  (cells). Since CA-2 delivered more than it produced, it dismantled its cells, shrunk and became atrophic.  CA-2 may be saved when other processes supply it with the missing resources,  restoring the balance between production and delivery.  The present proliferon consists of three transitional CA. CA-2 is exposed to rising demand, while CA-3 and CA-4 remain isolated (set point =25).

Next, CA-3 delivered to CA-2 its daily production. Since production equals delivery, CA-3 structure does not  change. CA-2 somewhat benefited from the delivery, nevertheless it became atrophic.

Next, CA-3 raised its delivery to CA-2. Initially  both benefited, however since CA-3 daily delivery > daily production, it shrunk, delivered less, and CA-2 also shrunk. CA-4 remained isolated
In the last experiment CA-3 and CA-4 delivered their daily production to CA-2, and  protected it from atrophy.

Is a measure of proliferon vigor (health) and is proportional to its resources.  Tolerance accumulation in isolated CA is the fastest, and will serve as reference (100%).  The rising demand on CA-2,  slows down its tolerance accumulation. The change = 52%  is expressed for the entire proliferon.  In the third experiment production delivery by CA-3  raises relative tolerance change to 37%.  When CA-2 and CA-3 become atrophic tolerance raises only by 0.4%. In the last experiment relative tolerance = 25% 




0. CA-2 = CA-3 = CA-4 = Isolated                                                                                                 


1. CA-2 {Production < Delivery}; CA-3  = CA-4 = Isolated                                                


2. CA-2 {Production < Delivery}; CA-3 -> CA-2 {Production = Delivery}; CA-4 = Isolated         


3. CA-2 {Production < Delivery}; CA-3 -> CA-2 {Production < Delivery}; CA-4 = Isolated         


4. CA-2 {Production < Delivery}; CA-3 -> CA-2 {Production = Delivery}


                                                       CA-4 -> CA-2 {Production = Delivery}                                      


In the isolated proliferon resource accumulation is the fastest. It declines during  interaction with the environment. When facing a rising demand the proliferon creates a new solution (here atrophy) and its tolerance accumulation rate declines.  The four experiments illustrate four types of solutions and their merit. The next table provides tolerances for a three CA proliferon. The isolated CA in the above table account for the better tolerances. Isolated CA are pure tolerance accumulators.



0. CA-2 = CA-3 = Isolated                                                                                      


1. CA-2 {Production < Delivery};                                         


2. CA-2 {Production < Delivery}; CA-3 -> CA-2 {Production = Delivery}


3. CA-2 {Production < Delivery}; CA-3 -> CA-2 {Production < Delivery}


It is obvious that the best strategy is not to divert any resources to the atrophic CA-2.