Tolerance accumulation

We continue with the previous experiment . The proliferon consists of three transient processes, CA-2,CA-3,CA-4. The sentinel process , CA-2, is injured, and CA-4 controls the resource quantity delivered to CA-2. Actually CA-4 controls the well being of the proliferon. The more resources it accumulates, the healthier it is. We may thus distinguish between several types of CA. The first is isolated, and the fastest resources (tolerance) accumulator.The next to it is a good producer, yet does not accumulate tolerance. At the end of its cycle it dies and is replaced with a zygote which repeats the cycle.

 

This CA-2 does not die. After delivering its resources it keeps a small amount and then starts again. The narrow portion consists of non producing stem cells. Next to it is a CA-2 with medium production capacity and good accumulation.

CA structure is controlled by three processes:

1. CA-2 injury. f[state[5,1], extent=1, color=0]
2. CA-4 resources delivery to CA-2. {delivery threshold, 1, 20}
3. CA-1 (stem process) which controls the when CA-2 state will be replaced with that of CA-1. change state: f[state[2,i+1] state[1,k]] {k,1,46}.

Since the timing of CA-2 injury does not change. The interaction between the three CA generates 46*20*4 solutions, each with its particular tolerance gaining capacity. It is summarized by the tolerance gain surface.

When CA-4 delivery threshold is low, processes lose tolerance and some become atrophic . As the threshold rises the proliferon gains more tolerance (resources). The same holds for any CA number. Given a process set with n members arranged in a loop. Resources are delivered in one direction . The sentinel process[1] is injured, and gets its resources from process[n], which controls resource delivery. The stem process controls the timing of change state in process[1].

Medical interpretation

The tolerance gain surface has several medical interpretations which are explained in the chapter A New Kind of Medicine. You might start with the glossary.

The surface illustrates two WOB meanings:
1. It is a process set (46*20*n).
2. It holds a knowledge to make this set a solutions set.

The third meaning, optimization, is still open. Looking at the surface you might conclude that WOB maximizes tolerance gain. However WOB optimization is more than that. It has the following objectives:
1. Maximize tolerance gain (health), AND
2. Maximize learning, experience, creativity (interaction), AND,
3. Minimize vulnerability.

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