Intermittent stimulation

We continue exploring ways to enhance tolerance accumulation. The previous experiment illustrated a continuous mutual stimulation of two CA. The present one demonstrates an intermittent mutual stimulation.

The parameters are:

delivery activation: [state[1, set point = p[1] - 0.1, state[0,1]];
delivery: [2,1, While[p[1] > set point], 2];
change state: [state[1, i+1] = state[0. 1], state[0, 1]];
change state: [state[2, i+1] = state[0. 1], state[0, 1]];
If[ p[1] > p[2], augment state: [state[2,i+1] += state[1, i]] 
If[ p[2] > p[1], augment state: [state[1,i+1] += state[2, i]]

The CA swing between two states, mutual stimulation and rest in which they are isolated. During stimulation, tolerance is accumulated fast, and during the resting period it is constant and slow. Since the tolerance gained during stimulation is lost, the overall (average) tolerance accumulation rate is constant.

This behavior reminds of an action potential.
The tolerance accumulation rate surface is rugged. The peaks are points of mutual stimulations when tolerance accumulation is accelerated, They are separated by areas of rest when the accumulation rate is constant (9.79) . Unlike in the previous experiments , here tolerance is always gained.

The white area underlying the contour plot is the constant tolerance accumulation rate of 9.79. The contours are accelerated accumulation rates.. The arrow points to an deceleration rate gradient extending from a high at {1, 46} to a low at {46, 1}.