Differentiation is defined as change in structure which involves two processes: 1. Change of the cell itself, 2. Change of the spatial relationship between cells. The first is manifested by a change in aging velocity. The second  is determined by age max.  The structure of a CA  whose max age is infinite is defined here as lowest (smallest)  differentiation.  Only  isolated CA display this property. Minimal differentiation is a triplet: {state, rule, max age = infinite}.By default the triplet defining a CA is also its differentiation.

Any interaction   which rescues the CA from its isolation, induces differentiation. Perturbations like, somatic, and age injuries, are differentiations. The outcome of a differentiation is unpredictable and therefore creative. Over a longer time span differentiation may seem predictable, like the transition from zygote to adult. Yet on the micro-scale it is unpredictable and  therefore creative.

In the next experiment, cells start aging at the same velocity like the CA above. At t = 30, aging acceleration was negative. For a while the CA continues differentiating as above, while its condition (health) starts deteriorating. Shortly before dying it is rescued by a zygote which matures into an minimally differentiated CA, alas, the age of its cells is zero. This CA will never respond to max age lowering. It might be rescued form its 'unhealthy' state, by injuring its structure.  You may regard it as a CA spore

Setup
zygote -> effect[no, 1000]; go[63]; restoreparams;  age[[no]] +=  a[[no]]; If[no == 1, age[[no]] += (toamplify  a[[2]] ); toamplify = 2.5; effect[1, 144];  effect[1, 1144]; go[100]; restore params; toamplify = 2.5; If [ j==30, toamplify  = -2]; effect[1, 144];  effect[1, 1144];
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