Health-2
Biological age
is the fundamental concept of the present study ch11,
ch12, ch57
ch66. Aging is viewed as an ongoing accumulation of resources
for sustaining life. Biological age is related with health which also depends on
resources accumulated by the organism. Yet health is more than just
biological age. Health depends also on how fast these resources are mobilized following injury.
We start with three CA with the same age
structure. CA-1 and CA-2 exchange resources (biological age). When CA-1
age is lower than CA-2, the latter feeds it with the missing resources
(biological age) and vice versa. In addition, CA-1 receives resources
from CA-3. Before the experiment starts the system is isolated and maintains
an equilibrium (homeorhesis). The three CA have the same age structure
Before injury, both CA have the same age structure. Injury
depletes age (resources) and Max[age] of the injured CA declines. CA-1 age
is replenished rapidly, since it gets resources from CA-2 and CA-3. CA-2 age is replenished slowly , since
it drives resources only from CA-1.
The last figure depicts system age. Following CA-1 injury the system mobilizes more resources
and mobilizes them faster,
than following CA-2 injury. The
first response is therefore healthier.
Setup:
nca=3; zygote
-> effect[no 1000]; go109]; restoreparams; injurystate[1, j, 30, 30,
f[[1, 1,]], 10, 1]; injuryage[1, j, 30, 30, f[[1, 1,]], 10, 0]; support[1,
2]; support[ 2, 1]; support[ 1,3]; go[100]; restoreparams; support[1, 2];
support[ 2, 1]; injurystate[2, j, 30, 30, f[[2, 1,]], 10, 1]; injuryage[2,
j, 30, 30, f[[2, 1,]], 10, 0]; go
[100];