Process fission-2

In two previous experiments two mechanisms of process fission were studied (1 ; 2). The present version seems the most appropriate, since it simulates cell turnover in the body .  A zygote is planted.  The stem process   evolves, and at t = 17 it matures and starts oscillating. The state which it attains at t = 63 is state one of the  process cycle  whose period is 46 at this state CA-1  enters mitosis and generates a CA-2 stem cell.  After a while CA-2 is killed (by the observer) When  CA-1 reaches state one it enters mitosis and creates a new stem cell. The two process system is a proliferon .

In the following experiment CA-2 is not killed. Whenever CA-1 enters mitosis it plants a stem cell in the existing CA-2. Now mitosis causes CA-2 injury. In this experiment mitosis did not change the CA-2 structure, Some states in the CA-2 cycle are not affected by stem cell planting.

In the next experiment,  following CA-2 planting, its state one in the cycle was delayed. Now  CA-1 mitosis hits other CA-2 states and changes its structure.

There are  four kinds of outcome after mitosis injures a state:
1. No change, like in the firts experiment
2. A new stationary oscillating CA
3. Chaotic oscillations
4. Death which is followed by another mitosis

Zygote and stem cell

Both have the same structure (=1), yet their ages differ. Zygote age = 0, and stem cell age > 0. A zygote generates a stem process and later on, a proliferon, while a stem cell generates a transient process. As long as the stem process exists, a dead transient process will be replaced by a new stem cell. Once  stem process is killed, the entire unit disappears. When a zygote divides into two zygotes, it generates two proliferons, by a symmetric division.  Mitosis which generates a stem cell is an asymmetric division, since the new process is transient, and differentiates, while the stem process does not differentiate.  Like in the above experiment when mitosis injured CA-2 and changed its structure, which is differentiation.

'Object oriented' process

Stem cell inherits all stem process properties. Exactly as an objects in object oriented programming. While in OOP objects maintain their structure. Here  objects evolve. In this context, process oriented programming (POP)  may be regarded as an extension of OOP, a super OOP.

Genotype and phenotype

Zygote is represented by the triplet {state = 0; rule = 600, age = 0}. It may be regarded as a gene from which a proliferon evolves. Yet this blueprint does not specify  proliferon behavior. This example illustrates the common fallacy of medicine, which claims that gene structure (the human genome) suffices for  understanding disease (phenotype).

Further reading:
Proliferon as a JAVA program (streaming tissues)

restoreparams[1,1,1]; restoreparams[2,1,1]; ++stateno[[no]]; If [nowdat[[no,8]] = 25, stateno[[no]] = 1];  If[stateno[[1]] == 1, newzygote[[2]]];

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