Protein synthesis

A protein is born at the gene site. As it matures it streams away from its birth place, and upon reaching its graveyard, it is catabolized. (v. Streaming proteins). This history will now be portrayed with CA. Each CA-1 state is a gene coding for a specific protein. When state-1 (gene-1) is activated, it  creates a CA-2 bud or RNA which assembles the first peptide. CA-2 is a history of an emerging protein. It starts as a peptide which polymerizes as it goes. Its voyage is described in the chapter on Streaming proteins

Directed turnover

Proteins turn over in a non-random fashion. First the molecule matures, and only then it is catabolized. In a random turnover each state would disappear randomly. .Protein turnover is directed, and obeys the FI-FO rule, First in, is also the first out, .Not only proteins, but all constituents of the organism behave this way, which makes life different from the inorganic world. At any instant, all stages of the evolving protein exist in the body. In the healthy organism, protein formation rate equals its catabolic rate. The organism maintains a steady state, or homeostasis. In order to highlight the fact that all constituents stream, this condition ought to be called homeorhesis (rhesis = stream).

Gene amplification

Each cycle generates one protein molecule. In order to produce more, CA-1 might cycle somewhat faster. It may also  create a new protein assembly line. The stem process, divides symmetrically,  creating another stem process engaged in protein production,  which is known as gene multiplication.

In order to produce other proteins, CA-1 initiates forms the CA-2 bud at other states.

To make these arguments more plausible, each state was flanked by black non-coding sequences (2 = G)

The first four states are drawn sequentially. Compare with chapters  on CA-insulin , and Knockout CA

These experiments might imply that CA-1 can generate only transient processes with 46 states. Here is one with 88 states

restoreparams[1,1,1]; restoreparams[2,2,1]; If [stateno[[1]]==35, a[[2]]+=a[[1]]]; go[160]

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